Obesity Research Today is a free monthly online journal that collates and summarizes the latest research about Obesity, including details on health, diet, prevention, exercise. | ||||||||
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Calcium intake and its relationship with adiposity and insulin resistance in post-pubertal adolescents.dos Santos LC, de Pádua Cintra I, Fisberg M, Martini LA Nutrition Department, School of Public Health, São Paulo University, São Paulo, Brazil. BACKGROUND: Dietary calcium intake has been described as being a negative contributor to adiposity. In adolescents, this relationship is not well established. The objectives of the present study were to compare the calcium intake of normal-weight and obese adolescents and to evaluate its relationship with adiposity and insulin resistance. METHODS: A cross-sectional analysis of 96 post-pubertal adolescents; 47 normal weight and 49 obese, mean age 16.6 (SD +/- 1.3) years. Body composition was assessed by dual-energy X-ray absorptiometry. Dietary intake was evaluated using a 3-day dietary record. The biochemical evaluation comprised the measurements of serum lipids, lipoproteins, glucose and insulin. Insulin resistance was calculated using the Homeostasis Model Assessment of Insulin resistance (HOMA-IR). RESULTS: The mean calcium intake, adjusted for energy, was lower in obese adolescents, 585.2 (+/-249.9) mg, than in normal weight adolescents, 692.1 (+/-199.5) mg. Only 4% of adolescents had an adequate intake of calcium. Calcium intake was inversely associated with body trunk fat, insulin and HOMA-IR in the obese group. The quartile analysis of calcium intake provided evidence that girls in the highest quartile had decreased adiposity and insulin resistance. CONCLUSIONS: This study showed a negative relationship between calcium intake and body fat and insulin resistance, mainly in obese girls, and demonstrates the importance of an increased dietary calcium intake. Published 14 March 2008 in J Hum Nutr Diet, 21(2): 109-16.
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